In biology a blind pan is a powerful technique that allows you to obtain ligands for structures that are not well characterized, as well as bypass issues like protein denaturation that plague typical pans against a purified protein target bound to a plate.

Crackle Gene is a user-friendly tool for comparing two complete prokaryotic genomes and pinpointing exactly what changed between them — down to the individual base, and up to the biological consequence of that change. You give it a reference genome and an evolved (or otherwise modified) genome, and it tells you where they differ, whether each difference falls inside a gene, and what that difference does to the encoded protein.